产品
编 号:F618370
分子式:C20H18BN3O3
分子量:359.19
产品类型
结构图
CAS No: 2379279-96-4
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产品详情
生物活性:
HSD1590 is potent ROCK inhibitor, with IC50s of 1.22 and 0.51 nM for ROCK1 and ROCK2, respectively. HSD1590 exhibits single digit nanomolar binding to ROCK (Kds<2 nM). HSD1590 displays low cytotoxicity.
体外研究:
HSD1590 (0.5-1 μM; 24 hours) exhibits an impressive attenuation in migration.HSD1590 (0.5-10 μM; 12-24 horus) shows that the excellent migration inhibition observed is not due to cell death, but inhibition of live cell migration.