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编 号:F618185
分子式:C24H23F3N4O3S
分子量:504.52
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.

体外研究:
CCR6 inhibitor 1 (化合物 35) 抑制 L20 诱导的人 B 细胞迁移。
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