产品
编 号:F617704
分子式:C3H10NO2P
分子量:123.09
产品类型
结构图
CAS No: 103680-47-3
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产品详情
生物活性:
3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of GABA. 3-Aminopropylphosphinic acid is a potent, selective GABAB receptor agonist.
体内研究:
3-Aminopropylphosphinic acid (5 mg/kg; i.v.) blocks the inhibitory effects of GABA against vagal broncho-spasm in guinea pigs.Animal Model:guinea pigs
Dosage:5 mg/kg
Administration:IV
Result:Blocked the inhibitory effects of GABA against vagal broncho-spasm.
体外研究:
3-Aminopropylphosphinic acid (10 μM) causes a concentration-dependent inhibition of the cholinergic twitch contraction in the electrically stimulated ileum (IC50=1.84-0.23 μM)3-Aminopropylphosphinic acid acts as an anti-aging substance for skin.