产品
编 号：F617167
分子式：C22H29NO3
分子量：355.47
分子式：C22H29NO3
分子量：355.47
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CAS No: 118111-54-9
产品详情
生物活性：
Cyprodime is a selective μ opioid receptor (MOR) antagonist with Kis of 5.4, 244.6, and 2187 nM for μ, δ, and κ, respectively.
体内研究：
Cyprodime (0.003-1 mg/kg; i.v.) do not significantly change the control bladder capacity during repeated acetic acid (AA) cystometrogram (CMG) but significantly reduces tibial nerve stimulation (TNS) inhibition starting from the 0.1 mg/kg dose and completely eliminates the inhibition induced by both 2 T and 4 T TNS at doses of 0.3-1 mg/kg.
Cyprodime is a selective μ opioid receptor (MOR) antagonist with Kis of 5.4, 244.6, and 2187 nM for μ, δ, and κ, respectively.
体内研究：
Cyprodime (0.003-1 mg/kg; i.v.) do not significantly change the control bladder capacity during repeated acetic acid (AA) cystometrogram (CMG) but significantly reduces tibial nerve stimulation (TNS) inhibition starting from the 0.1 mg/kg dose and completely eliminates the inhibition induced by both 2 T and 4 T TNS at doses of 0.3-1 mg/kg.
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