产品
编 号：F617144
分子式：C14H17ClN2O2
分子量：280.75
分子式：C14H17ClN2O2
分子量：280.75
产品类型
规格
价格
是否有货
结构图
CAS No: 118702-11-7
产品详情
生物活性：
TIK-301 (PD-6735) is a chlorinated melatonin derivative and a potent, high-affinity and orally active melatonin MT1 and MT2 receptors agonist with Kis of 0.081 nM and 0.042 nM, respectively. TIK-301 is also a 5-HT2B/5-HT2C receptors antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment.
体内研究：
In male rats, TIK-301(at doses of 0.8 and 4.0 mg/kg/day) can reduce body weight, and without altering food intake.The Tmax and half-life of TIK-301 is 1.1 hour and 1 hour, respectively.
TIK-301 (PD-6735) is a chlorinated melatonin derivative and a potent, high-affinity and orally active melatonin MT1 and MT2 receptors agonist with Kis of 0.081 nM and 0.042 nM, respectively. TIK-301 is also a 5-HT2B/5-HT2C receptors antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment.
体内研究：
In male rats, TIK-301(at doses of 0.8 and 4.0 mg/kg/day) can reduce body weight, and without altering food intake.The Tmax and half-life of TIK-301 is 1.1 hour and 1 hour, respectively.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备