产品
编 号：F616379
分子式：C23H26N2O6
分子量：426.46
分子式：C23H26N2O6
分子量：426.46
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 139225-22-2
产品详情
生物活性：
Panamesine (EMD 57445) is a sigma receptor ligand, which has a high affinity (IC50 6 nM) and selectivity for sigma binding sites. Panamesine is a potential atypical neuroleptic agent.
体内研究：
Panamesine (EMD 57445; 0.3, 1, 3, 30 mg/kg) induces a dose-dependent increase of c-fos expression in several cortical areas with the strongest signals in the piriform cortex.Animal Model:Female Sprague Dawley rats aged 2 months with a body weights of 200-250 g
Dosage:0.3, 1, 3, 30 mg/kg
Administration:Subcutanous injections
Result:Specific c-fos gene expression was detected at all concentrations (0.3 mg/kg, 1 mg/kg, 3 mg/kg, 30 mg/kg) tested in frontal, parietal, perirhinal, temporal, piriform, insular, limbic, cingulate and occipital cortex.
Panamesine (EMD 57445) is a sigma receptor ligand, which has a high affinity (IC50 6 nM) and selectivity for sigma binding sites. Panamesine is a potential atypical neuroleptic agent.
体内研究：
Panamesine (EMD 57445; 0.3, 1, 3, 30 mg/kg) induces a dose-dependent increase of c-fos expression in several cortical areas with the strongest signals in the piriform cortex.Animal Model:Female Sprague Dawley rats aged 2 months with a body weights of 200-250 g
Dosage:0.3, 1, 3, 30 mg/kg
Administration:Subcutanous injections
Result:Specific c-fos gene expression was detected at all concentrations (0.3 mg/kg, 1 mg/kg, 3 mg/kg, 30 mg/kg) tested in frontal, parietal, perirhinal, temporal, piriform, insular, limbic, cingulate and occipital cortex.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备