产品
编 号:F616112
分子式:C17H16Cl2N2O2
分子量:351.23
产品类型
结构图
CAS No: 147362-57-0
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产品详情
生物活性:
Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 μM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells.
体外研究:
Loviride (0.01 μM) inhibits HIV-1(IIIB) replication in MT-4 cells, also inhibits HIV-2 and SIV, with EC50s of 85.5, 7.4 μM for HIV-2 (ROD), HIV-2 (EHO), and 11.4, 28.5, 57.0 μM for SIV (mac251), SIV (agm3), SIV (mndGB1), respectively.