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编 号:F615842
分子式:C20H29NO4S2
分子量:411.58
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生物活性:
(R)-SCH 42495 is the less active enantiomer of SCH 42495. SCH 42495 is an orally active neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally active ethylester proagent of SCH 42354.

体内研究:
Inhibition of NEP in vivo has been shown to produce beneficial vasodilatory and natriuretic responses.

体外研究:
NEP acts as a critical enzyme in the degradation. NEP cleaves atrial natriuretic factors (ANF) in vitro.
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