产品
编 号：F615835
分子式：C16H16K3O7PS
分子量：500.63
分子式：C16H16K3O7PS
分子量：500.63
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 157124-84-0
产品详情
生物活性：
BPH-652 is a S. aureus dehydrosqualene synthase (CrtM) inhibitor, with a Ki of 1.5 nM and an IC50 of 100-300 nM (S. aureus pigment formation).
体内研究：
BPH-652 treatment (0.5 mg twice per day (days ?1, 0, 1, and 2), Intraperitoneal injection) significantly lowers S. aureus bacterial counts in the kidneys of the mice than those of the control group (P < 0.001), with 8 of 13 below the detection threshold, versus only 2 of 14 in the control group; on average, this result corresponds to a 98% decrease in surviving bacteria in the treatment group.Animal Model:A systemic S. aureus infection model in mice.
Dosage:0.5 mg twice per day (days ?1, 0, 1, and 2).
Administration:Intraperitoneal injection.
Result:S. aureus bacterial counts in the kidneys of the mice treated with BPH-652 were significantly lower than those of the control group.
BPH-652 is a S. aureus dehydrosqualene synthase (CrtM) inhibitor, with a Ki of 1.5 nM and an IC50 of 100-300 nM (S. aureus pigment formation).
体内研究：
BPH-652 treatment (0.5 mg twice per day (days ?1, 0, 1, and 2), Intraperitoneal injection) significantly lowers S. aureus bacterial counts in the kidneys of the mice than those of the control group (P < 0.001), with 8 of 13 below the detection threshold, versus only 2 of 14 in the control group; on average, this result corresponds to a 98% decrease in surviving bacteria in the treatment group.Animal Model:A systemic S. aureus infection model in mice.
Dosage:0.5 mg twice per day (days ?1, 0, 1, and 2).
Administration:Intraperitoneal injection.
Result:S. aureus bacterial counts in the kidneys of the mice treated with BPH-652 were significantly lower than those of the control group.
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