产品
编 号：F615693
分子式：C5H8Cl2N2O3
分子量：215.03
分子式：C5H8Cl2N2O3
分子量：215.03
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 161922-40-3
产品详情
生物活性：
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.
体内研究：
Acivicin hydrochloride (AT-125 hydrochloride；5 mg/kg；腹腔注射；每周两次) 将尿 γ-GT 降低 70-78%。Animal Model:Male pigmented Long-Evans rats weighed between 250 g and 300 g exposed to Toluene
Dosage:5 mg/kg
Administration:IP; twice weekly (monday and wednesday)
Result:Reduced urinary γ-GT by 70-78%.
体外研究：
Acivicin hydrochloride (AT-125 盐酸盐；0.1-50 μM；5 天) 在人 HepG2 细胞中的 IC50 为 0.7 μM。
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.
体内研究：
Acivicin hydrochloride (AT-125 hydrochloride；5 mg/kg；腹腔注射；每周两次) 将尿 γ-GT 降低 70-78%。Animal Model:Male pigmented Long-Evans rats weighed between 250 g and 300 g exposed to Toluene
Dosage:5 mg/kg
Administration:IP; twice weekly (monday and wednesday)
Result:Reduced urinary γ-GT by 70-78%.
体外研究：
Acivicin hydrochloride (AT-125 盐酸盐；0.1-50 μM；5 天) 在人 HepG2 细胞中的 IC50 为 0.7 μM。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备