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编 号:F615598
分子式:C64H104N13O22PS
分子量:1470.62
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生物活性:
Yp537 is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor.

体外研究:
Yp537 (5-50 μM; 1 h) abolishes the formation of the hER-ERE complex. And dose not inhibit the formation of the STAT1-serum-induced element complex.Yp537 binds to a SH2-like domain, and interferes with the SH2-like phosphopeptide coupling mechanism between hER monomers.
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