产品
编 号:F065355
分子式:C35H35N5O4
分子量:589.68
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1mg
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5mg
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10mg
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25mg
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生物活性:
PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively). PE154 can label β-amyloid plaques in histochemical analysis.

体内研究:
PE154 (hippocampus injection; 0.2 μg per mouse; once) can stain the histochemical of cortical βamyloid plaques.Animal Model:13–20-month-old triple-transgenic mice harbouring three mutant genes (APPswe, PS-1 and tauP301L)
Dosage:0.2 μg per mouse
Administration:Hippocampus injection; 0.2 μg per mouse; once
Result:Showed the histochemical staining of cortical βamyloid plaques in triple-transgenic (TTG) mice.
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