产品
编 号：F614786
分子式：C169H262N44O54S
分子量：3806.3
分子式：C169H262N44O54S
分子量：3806.3
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 196109-27-0
产品详情
生物活性：
Exendin (5-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. Exendin (5-39) improves memory impairment in β-amyloid protein-treated rats.
体内研究：
Exendin (5-39) (intracerebroventricular injection; 0.3 μg; once daily; 1-week) increases GLT-1 protein levels in the hippocampus of male Wistar rats. Additionally, hippocampal slices are prepared from Ex-treated or vehicle rats,Exendin (5-39) decreases fEPSP decay time and increases the input-output relation and decreased the paired-pulse ratio in the dentate gyrus (DG). Furthermore, Ex inhibits long-term depression but not long-term potentiation in the DG.Animal Model:Wistar rats (3 weeks old and 18 days pregnant)
Dosage:0.3 μg
Administration:Intracerebroventricular injection; 0.3 μg; once daily; 1-week
Result:Inhibited GLT-1 protein levels and inhibited long-term depression in rats.
Exendin (5-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. Exendin (5-39) improves memory impairment in β-amyloid protein-treated rats.
体内研究：
Exendin (5-39) (intracerebroventricular injection; 0.3 μg; once daily; 1-week) increases GLT-1 protein levels in the hippocampus of male Wistar rats. Additionally, hippocampal slices are prepared from Ex-treated or vehicle rats,Exendin (5-39) decreases fEPSP decay time and increases the input-output relation and decreased the paired-pulse ratio in the dentate gyrus (DG). Furthermore, Ex inhibits long-term depression but not long-term potentiation in the DG.Animal Model:Wistar rats (3 weeks old and 18 days pregnant)
Dosage:0.3 μg
Administration:Intracerebroventricular injection; 0.3 μg; once daily; 1-week
Result:Inhibited GLT-1 protein levels and inhibited long-term depression in rats.
产品资料
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