产品
编 号：F613689
分子式：C25H27N3O5
分子量：449.5
分子式：C25H27N3O5
分子量：449.5
产品类型
规格
价格
是否有货
结构图
CAS No: 288247-87-0
产品详情
生物活性：
T-2513 is a selective topoisomerase I inhibitor. T-2513 binds covalently to and stabilizes the topoisomerase I-DNA complex and inhibits DNA replication and RNA synthesis, ultimately leading to cell death.
体内研究：
T-2513 (1-100 mg/kg) shows Antitumor Activity against Walker-256 carcinoma.Animal Model:Rats bearing Walker-256 carcinoma
Dosage:1, 10, and 100 mg/kg
Administration:
Result:The ED50 was 23 mg/kg.
体外研究：
SN-38 is the metabolite of T-2513.T-2513 has a broad cytotoxicity against a range of human tumor cell lines.
T-2513 is a selective topoisomerase I inhibitor. T-2513 binds covalently to and stabilizes the topoisomerase I-DNA complex and inhibits DNA replication and RNA synthesis, ultimately leading to cell death.
体内研究：
T-2513 (1-100 mg/kg) shows Antitumor Activity against Walker-256 carcinoma.Animal Model:Rats bearing Walker-256 carcinoma
Dosage:1, 10, and 100 mg/kg
Administration:
Result:The ED50 was 23 mg/kg.
体外研究：
SN-38 is the metabolite of T-2513.T-2513 has a broad cytotoxicity against a range of human tumor cell lines.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备