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编 号:F613603
分子式:C226H338N60O64S
分子量:4951.53
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生物活性:
(Pro3) GIP, human ((Pro3) Gastric Inhibitory Peptide, human) is an efficacious, stable and specific human GIP receptor (hGIPR) full agonist. (Pro3) GIP, human has high binding affinity for human GIPR with Ki/ Kd values of 0.90 nM. (Pro3) GIP, human can be used for the research of obesity-related diabetes.

体内研究:
(Pro3) GIP, human has comparatively weak partial agonist effect in rodent models.

体外研究:
(Pro3) GIP, human induces cAMP accumulation with an EC50 value of 0.026 nM.(Pro3) GIP, human has high binding affinity for human GIPR, Rat GIPR and Mouse GIPR with Ki/ Kd values of 0.90 nM, 1.1 nM and 0.72 nM, respectively.
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