产品
编 号:F613538
分子式:C25H18N4O2
分子量:406.44
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1mg
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5mg
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10mg
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25mg
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生物活性:
SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 μM for ST-hSK. SKI-I also inhibits hERK2 (IC50=11 μM). SKI-I induces apoptosis in tumor cell lines.

体外研究:
SKI-I (Compound I; 5 μg/mL) inhibits SK activity by 99%.SKI-I (10 μM; 24 h) induces the apoptosis of T24 cells.
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