产品
编 号：F613390
分子式：C37H71N3O8S
分子量：718.04
分子式：C37H71N3O8S
分子量：718.04
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 320725-47-1
产品详情
生物活性：
Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.
体内研究：
Squalamine is ineffective when administered intravitreally and therefore requires intravenous dosing. However, systemic dosing has yielded promising results in rats as well as humans.
体外研究：
Squalamine lactate has a more generalized effect on the cellular signaling cascade that is common to both VEGF and other growth factors. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin.
Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.
体内研究：
Squalamine is ineffective when administered intravitreally and therefore requires intravenous dosing. However, systemic dosing has yielded promising results in rats as well as humans.
体外研究：
Squalamine lactate has a more generalized effect on the cellular signaling cascade that is common to both VEGF and other growth factors. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin.
产品资料
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