产品
编 号:F065080
分子式:C22H27ClN4O5
分子量:462.93
产品类型
结构图
CAS No: 1191995-00-2
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产品详情
生物活性:
Dorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
体内研究:
Dorzagliatin (低剂量 10 mg/kg,高剂量 30 mg/kg;胃内给药;每天上午 8:00,持续一个月) 对糖尿病大鼠的血糖水平产生降糖作用[2。Animal Model:Male Sprague-Dawley (SD) rats (aged approximately 6–8 weeks and weighing 200-230?g)[2
Dosage:Low-dose (10?mg/kg), and high-dose (30?mg/kg)
Administration:Administered intragastrically (i.g.); daily (8:00 AM) for one month
Result:Exerted a glucose-lowering effect on the glucose levels.