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编 号:F613168
分子式:C71H99N19O15S
分子量:1490.73
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生物活性:
TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range.

体外研究:
TfR-T12 binds to the TfR and is subsequently internalized into TfR-expressing cells.TfR-T12 is a synthetic peptide obtained by phage display, and is able to bind a different site on TfRs compared with transferrin. TfR-T12 can be chemically conjugated with a pegylated lipid derivative, 3-(N-succinimidyloxyglutaryl)aminopropyl- polyethyleneglycol(2000)- carbamyl distearoyl phosphatidylethanolamine (NHS-PEG2000-DSPE), and used as a functional material to construct the multifunctional lipid vesicles.
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