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编 号:F613125
分子式:C23H20F2N5O5PS
分子量:547.47
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Fosravuconazole (BMS-379224), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole can be used for candidiasis, onychomycosis and parasitemia research.

体内研究:
Fosravuconazole (E-1224; 10-50 mg/kg; oral administration; daily; for 20 days) treatment suppresses the parasitemia and prevents death in mice infected with the T. cruzi Y strain.Animal Model:Swiss female mice (20-24 g) inoculated with trypomastigotes (Y strain).
Dosage:10 mg/kg, 20 mg/kg, 30 mg/kg, 40 mg/kg, 50 mg/kg
Administration:Oral administration; daily; for 20 days
Result:Suppressed the parasitemia and prevented death.

体外研究:
Ravuconazole has potent in vitro antifungal activity against a wide range of fungal species, including Candida, Aspergillus, and Trichophyton species.
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