产品
编 号:F610920
分子式:C145H238N34O44
分子量:3161.64
产品类型
结构图
CAS No: 852805-92-6
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产品详情
生物活性:
TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke.
体外研究:
TRAF6 peptide (150 μM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells.TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro.