产品
编 号:F610710
分子式:C48H71N13O20
分子量:1150.15
产品类型
结构图
CAS No: 864915-61-7
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产品详情
生物活性:
HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.
体外研究:
The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists.