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编 号:F610189
分子式:C24H18ClFeN3O
分子量:455.72
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
SARS-CoV-IN-2 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-2 shows anti-Coronavirus activity with an EC50 of 1.9 μM in Vero cells. SARS-CoV-IN-2 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 21.5 and 30 nM; and IC90s of 51.0 and 99.9 nM; respectively. SARS-CoV-IN-2 reduces HIV-1-induced cytopathic effect with an EC50 of 2.9 μM in MT-4 cells. Antimalarial and Antiviral Activities.

体外研究:
SARS-CoV-IN-2 (Compound 3) inhibits in vitro growth of Plasmodium falciparum far better than Chloroquine (CQ) .
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