产品
编 号:F609825
分子式:C60H98N16O20S
分子量:1395.58
产品类型
结构图
CAS No: 916977-43-0
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产品详情
生物活性:
Peptide5, a connexin 43 mimetic peptide, reduce animals swelling, astrogliosis, and neuronal cell death after spinal cord injury
体内研究:
Peptide5 is could be used to treat traumatic spinal cord injured rats.
体外研究:
Peptide5, significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model. Peptide5 produces the more significant reduction in swelling and is analyzed further. Treatment with peptide5 reduced both the level of Cx43 and the number of glial fibrillary acidic protein (GFAP)-positive astrocytes, and at the same time reduces the loss of NeuN- and SMI-32–positive neurons in a concentration- and time-dependent manner.