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编 号:F609427
分子式:C24H20ClN5O
分子量:429.9
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CAS No: 946293-78-3
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生物活性:
Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively.