产品
编 号:F608646
分子式:C15H9NO3
分子量:251.24
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
联系客服
产品详情
生物活性:
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 values ranging from 16 μM to 120 μM. MLS000532223 prevents GTP binding to several GTPases.

体外研究:
MLS000532223 prevents GTP binding to several GTPases in a dose-dependent manner.MLS000532223 modulates Rho-family GTP-binding kinetics.MLS000532223 is active in cell-based assays and inhibits EGF-stimulated Rac 1 activation.MLS000532223 inhibits actin rearrangements and changes in cell morphology that are downstream of Rho family GTPase activation.MLS000532223 (10 μM) modulates actin remodeling in mast cells.MLS000532223 (10 μM) inhibits ligand-stimulated β-hexosaminidase secretion of RBL cells.
产品资料