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编 号:F606533
分子式:C20H32O5
分子量:352.47
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生物活性:
Thromboxane A2 (TXA2) is a prostanoid mediator produced by the metabolism of Arachidonic acid (HY-109590) through the cyclooxygenase pathway. Thromboxane A2 activates the thromboxane-prostanoid (TP) receptors. Thromboxane A2 is a potent vasoconstrictor eicosanoid. Thromboxane A2 (TXA2) leads to potent vasoconstriction by stimulation of smooth muscle cells. Thromboxane A2 acts as s tonic immunoregulator to regulate adaptive immune responses.

体外研究:
Thromboxane A2 (300 nM, 12 h) 可调节内皮细胞迁移、血管生成和肿瘤转移。
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