产品
编 号：F603032
分子式：C15H10O6
分子量：286.24
分子式：C15H10O6
分子量：286.24
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 520-30-9
产品详情
生物活性：
Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells.
体外研究：
Norartocarpetin has strong mushroom tyrosinase inhibitory activity with an IC50 value of 0.47 μM.Norartocarpetin (0-100 μM; 48 h) leds to dose-dependent cytotoxic effects in NCI-H460 cells and MRC-9 cells with IC50 values of 22 μM and 85 μM, respectively.Norartocarpetin (0, 11, 22, and 44 μM; 24 h) led to blockade of Ras/Raf/MAPK signalling pathway.Norartocarpetin (0, 11, 22, and 44 μM, 24 h) induced the apoptosis of the human lung carcinoma cells (NCI-H460).Norartocarpetin (0, 11, 22, and 44 μM) leds to S-phase cell cycle arrest.Norartocarpetin (22 μM; 24 h) leds to dose-dependent suppression of cell invasion.Norartocarpetin (0, 11, 22, and 44 μM, 24 h) leds to significantinhibition of cell migration.
Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells.
体外研究：
Norartocarpetin has strong mushroom tyrosinase inhibitory activity with an IC50 value of 0.47 μM.Norartocarpetin (0-100 μM; 48 h) leds to dose-dependent cytotoxic effects in NCI-H460 cells and MRC-9 cells with IC50 values of 22 μM and 85 μM, respectively.Norartocarpetin (0, 11, 22, and 44 μM; 24 h) led to blockade of Ras/Raf/MAPK signalling pathway.Norartocarpetin (0, 11, 22, and 44 μM, 24 h) induced the apoptosis of the human lung carcinoma cells (NCI-H460).Norartocarpetin (0, 11, 22, and 44 μM) leds to S-phase cell cycle arrest.Norartocarpetin (22 μM; 24 h) leds to dose-dependent suppression of cell invasion.Norartocarpetin (0, 11, 22, and 44 μM, 24 h) leds to significantinhibition of cell migration.
产品资料
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