产品
编 号：F601649
分子式：C22H28N2O2
分子量：352.47
分子式：C22H28N2O2
分子量：352.47
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
100mg
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询价
结构图
CAS No: 1467047-25-1
产品详情
生物活性：
SRS11-92, a Ferrostatin-1 (Fer-1) analogue, is a potent ferroptosis inhibitor. SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells (EC50=6 nM).
体内研究：
SRS11-92, used at 500 nM, is efficacious in protecting human and mouse cellular models of Friedreich ataxia (FRDA)treatedwith ferricammoniumcitrate (FAC) andaninhibitorofglutathione synthesis (BSO), whereas caspase-3 inhibitors fail to show significant biological activity.
体外研究：
SRS11-92 fully protects oligodendrocytes (OLs) from cystine deprivation when tested at 100 nM. SRS11-92 rescues primary human fibroblasts from death induced by frataxin knock-down.
SRS11-92, a Ferrostatin-1 (Fer-1) analogue, is a potent ferroptosis inhibitor. SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells (EC50=6 nM).
体内研究：
SRS11-92, used at 500 nM, is efficacious in protecting human and mouse cellular models of Friedreich ataxia (FRDA)treatedwith ferricammoniumcitrate (FAC) andaninhibitorofglutathione synthesis (BSO), whereas caspase-3 inhibitors fail to show significant biological activity.
体外研究：
SRS11-92 fully protects oligodendrocytes (OLs) from cystine deprivation when tested at 100 nM. SRS11-92 rescues primary human fibroblasts from death induced by frataxin knock-down.
产品资料
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