产品
编 号:F601437
分子式:C20H20N4O4
分子量:380.4
产品类型
结构图
CAS No: 2378173-15-8
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产品详情
生物活性:
PF-06928215 is a cGAS (cyclic GMP-AMP Synthase) inhibitor with an IC50 of 4.9 μΜ. PF-06928215 has a high binding affinity of 0.2 μM (Kd).
体外研究:
PF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression.