产品
编 号:F601411
分子式:C20H20Cl2N4O4
分子量:451.3
产品类型
结构图
CAS No: 2421118-05-8
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产品详情
生物活性:
JKE-1716 is a potent and selective nitrolic acid-containing GPX4 inhibitor. JKE-1716 is able of inducing ferroptosis selectively through covalent GPX4 inhibition.
体外研究:
JKE-1716 (0~100 nΜ; 72 hours; LOX-IMVI cells) inhibits cell viability.JKE-1716 (LOX-IMVI cells) inhibits the expression of α-GPX4.