产品
编 号:F601224
分子式:C29H32F3N5O5
分子量:587.59
产品类型
结构图
CAS No: 1068148-47-9
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产品详情
生物活性:
BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect.
体内研究:
BIBP3226 (0.5、5 μg;icv) 在较高剂量下诱导类似焦虑的作用。Animal Model:Male Wistar rats 270-350 g
Dosage:0.5, 5 μg
Administration:I.c.v
Result:At the dose of 5μg caused an anxiogenic-like effect while the lower dose was ineffective.