产品
编 号：F601142
分子式：C11H9Br4N3O2
分子量：534.82
分子式：C11H9Br4N3O2
分子量：534.82
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 1085822-09-8
产品详情
生物活性：
CK2/ERK8-IN-1 is a dual casein kinase 2 (CK2) (Ki of 0.25 μM) and ERK8 (MAPK15, ERK7) inhibitor with IC50s of 0.50 μM. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (homeodomain-interacting protein kinase 2), and DYRK1A with Kis of 8.65 μM, 15.25 μM, and 11.9 μM, respectively. CK2/ERK8-IN-1 has pro-apoptotic efficacy.
体外研究：
CK2/ERK8-IN-1 (Compound K66; 0-50 μM; 24 hours; Jurkat cells) treatment displays cytotoxic activity in Jurkat cells.
CK2/ERK8-IN-1 is a dual casein kinase 2 (CK2) (Ki of 0.25 μM) and ERK8 (MAPK15, ERK7) inhibitor with IC50s of 0.50 μM. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (homeodomain-interacting protein kinase 2), and DYRK1A with Kis of 8.65 μM, 15.25 μM, and 11.9 μM, respectively. CK2/ERK8-IN-1 has pro-apoptotic efficacy.
体外研究：
CK2/ERK8-IN-1 (Compound K66; 0-50 μM; 24 hours; Jurkat cells) treatment displays cytotoxic activity in Jurkat cells.
产品资料
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