产品
编 号:F601110
分子式:C16H16ClN3O6S
分子量:413.83
产品类型
结构图
CAS No: 1523437-16-2
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生物活性:
ML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic cell burden.