产品
编 号：F600931
分子式：C206H324N56O65
分子量：4625.11
分子式：C206H324N56O65
分子量：4625.11
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 475221-20-6
产品详情
生物活性：
NEP(1-40) is a Nogo-66 receptor (NgR) antagonist peptide, reversing the injury-induced shift in distribution of microglia morphologies by limiting myelin-based inhibition.
体内研究：
NEP(1-40) (89 μg/kg, ip, 15 min and 19 h post-injury) administration further shifts distributions of microglia away from an injury-induced activated morphology towards greater proportions of rod and macrophage-like morphologies.Animal Model:74 male Sprague-Dawley rats (328-377 g).
Dosage:89 μg/kg (97.5% PBS and 2.5% DMSO).
Administration:IP, 15 min and 19 h post-injury.
Result:Reduced NgR function immediately post-injury.Increased number of amoeboid microglia/macrophages at 2 days post-injury
NEP(1-40) is a Nogo-66 receptor (NgR) antagonist peptide, reversing the injury-induced shift in distribution of microglia morphologies by limiting myelin-based inhibition.
体内研究：
NEP(1-40) (89 μg/kg, ip, 15 min and 19 h post-injury) administration further shifts distributions of microglia away from an injury-induced activated morphology towards greater proportions of rod and macrophage-like morphologies.Animal Model:74 male Sprague-Dawley rats (328-377 g).
Dosage:89 μg/kg (97.5% PBS and 2.5% DMSO).
Administration:IP, 15 min and 19 h post-injury.
Result:Reduced NgR function immediately post-injury.Increased number of amoeboid microglia/macrophages at 2 days post-injury
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