产品
编 号:F600570
分子式:C15H16N2O4
分子量:288.3
产品类型
结构图
CAS No: 346691-38-1
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产品详情
生物活性:
STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). STING-IN-2 can be used for autoinflammatory disease research.
体外研究:
THP-1 cells are pretreated with STING-IN-2 (C-170; 0.5 μM) and stimulated with cGAMP. STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels.