产品
编 号:F599888
分子式:C24H14O5
分子量:382.36
产品类型
结构图
CAS No: 41307-63-5
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生物活性:
Resorcinolnaphthalein is a specific angiotensin-converting enzyme 2 (ACE2)?enhancer and activates ACE2 activity with an EC50 value of 19.5 μM. Resorcinolnaphthalein can be used for the investigation of hypertension and renal fibrosis.
体外研究:
Resorcinolnaphthalein (100 μM) andXNT enhances ACE2 activity in a dose-dependent manner with EC50 values of 19.5 μM and 20.1 μM, respectively.ACE2 is an effective enzyme in attenuating fibrosis and structural remodeling. Enhancement of ACE2 activity has beneficial effects on the cardiovascular system and protects against hypertension induced pathophysiology.