产品
编 号:F597617
分子式:C31H30ClN5O3S2
分子量:620.18
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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50mg
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生物活性:
WEHI-539 hydrochloride is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM.

体外研究:
WEHI-539 hydrochloride is a selective inhibitor of Bcl-XL. WEHI-539 augments NSC 241240 induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells.
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