产品
编 号：F595308
分子式：C5H21N3O8P2
分子量：313.18
分子式：C5H21N3O8P2
分子量：313.18
产品类型
规格
价格
是否有货
500μg
询价
询价
结构图
CAS No: 443892-56-6
产品详情
生物活性：
HDMAPP triammonium is a potent phosphoantigen in the ammonium form and the pyrophosphate form of (E)-HDMAPP. HDMAPP is also a potent activator of γδ T cells and can induce T cell stimulation in vitro (EC50=0.39 nM, TNF-α).
体内研究：
HDMAPP triammonium (化合物 3E) (0.02-2.5 mg/kg；静脉注射；15 天) 显着增加食蟹猴模型中的 γδ 细胞。Animal Model:Nonhuman Primate Model in Cynomolgus
Dosage:0.02 mg/kg, 0.1 mg/kg, 0.5 mg/kg, 2.5 mg/kg
Administration:Intravenous injection; once with daily s.c. low doses IL-2 to sustain γδ-T-cell proliferation, for 15 days
Result:Significantly increased γδ-cells in vivo at 0.02 mg/kg. Reached maximal effect at 2.5 mg/kg.
体外研究：
HDMAPP triammonium (化合物 3E) (2 μM) 增加原代多克隆人 Vγ9Vδ2 T 细胞中的 TNF-α 释放水平，并具有刺激性生物活性。
HDMAPP triammonium is a potent phosphoantigen in the ammonium form and the pyrophosphate form of (E)-HDMAPP. HDMAPP is also a potent activator of γδ T cells and can induce T cell stimulation in vitro (EC50=0.39 nM, TNF-α).
体内研究：
HDMAPP triammonium (化合物 3E) (0.02-2.5 mg/kg；静脉注射；15 天) 显着增加食蟹猴模型中的 γδ 细胞。Animal Model:Nonhuman Primate Model in Cynomolgus
Dosage:0.02 mg/kg, 0.1 mg/kg, 0.5 mg/kg, 2.5 mg/kg
Administration:Intravenous injection; once with daily s.c. low doses IL-2 to sustain γδ-T-cell proliferation, for 15 days
Result:Significantly increased γδ-cells in vivo at 0.02 mg/kg. Reached maximal effect at 2.5 mg/kg.
体外研究：
HDMAPP triammonium (化合物 3E) (2 μM) 增加原代多克隆人 Vγ9Vδ2 T 细胞中的 TNF-α 释放水平，并具有刺激性生物活性。
产品资料
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