产品
编 号:F595047
分子式:C15H12O7
分子量:304.25
产品类型
结构图
CAS No: 917091-74-8
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产品详情
生物活性:
Globosuxanthone A is a dihydroxanthenone with obvious antifungal activity towards Fusarium graminearum, Fusarium solani, and Botrytis cinerea with MIC values of 4, 8, and 16 μg/mL, respectively. Anticancer activity.
体外研究:
Globosuxanthone A shows cytotoxicities against NCI-H460, MCF-7, SF-268, PC-3, PC-3M, LNCaP, DU-145 cells (IC50=0.65-3.6 μM).Globosuxanthone A impairs cell cycle progression of NCI-H460 and PC-3M cells leading to accumulation in the G2/M and S phases .