产品
编 号:F594507
分子式:C19H34O2
分子量:294.47
产品类型
结构图
CAS No: 738-87-4
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产品详情
生物活性:
Sterculic acid is a stearoyl-CoA desaturase-1 (SCD1) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase (Δ9D) activity with an IC50 value of 0.9 μM.
体内研究:
Sterculic acid has been proposed as a potential tool for the treatment of metabolic syndrome (MS) since it inhibits the activity of the stearoyl-CoA desaturase-1 (SCD1) in vivo.
体外研究:
Sterculic acid (SA) is a cyclopropene fatty acid originally found in the seeds of the plant Sterculia foetida with numerous biological activities.Sterculic acid is able to reduce adrenomedullin expression (AP, RP, APS, IML, in preparation).Sterculic acid is also able to mediate anti-inflammatory and protective effects.Sterculic acid has a potent luteolytic effect in ovines by inhibition in the synthesis of progesterone, which causes luteal regression.