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编 号：F580447
分子式：C17H21NO
分子量：255.35
分子式：C17H21NO
分子量：255.35
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CAS No: 92-12-6
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生物活性：
Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity (Ki: 160 nM).
体外研究：
Phenyltoloxamine (10-50 μM, 24 h) demonstrates cytotoxicity in EVSA-T cells.Phenyltoloxamine exhibits potent Sigma 1 Receptor (S1R) binding affinity with a Ki value of 160 nM.Phenyltoloxamine (100 μM) inhibits human liver macrosaml CYP2D6 enzyme by 99.0%.
Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity (Ki: 160 nM).
体外研究：
Phenyltoloxamine (10-50 μM, 24 h) demonstrates cytotoxicity in EVSA-T cells.Phenyltoloxamine exhibits potent Sigma 1 Receptor (S1R) binding affinity with a Ki value of 160 nM.Phenyltoloxamine (100 μM) inhibits human liver macrosaml CYP2D6 enzyme by 99.0%.
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