产品
编 号：F578127
分子式：C21H18N4O3
分子量：374.39
分子式：C21H18N4O3
分子量：374.39
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 874484-20-5
产品详情
生物活性：
S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production.
体内研究：
S29434 (1 和 15 mg/kg；ip 一次) 影响对物体识别记忆。Animal Model:CH3 wild-type mice
Dosage:1 and 15 mg/kg
Administration:Intraperitoneal injection; 1 and 15 mg/kg once
Result:Positively affected memory by inhibiting QR2.
体外研究：
S29434 (5-10 μM；24 h) 诱导 HepG2 细胞自噬。
S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production.
体内研究：
S29434 (1 和 15 mg/kg；ip 一次) 影响对物体识别记忆。Animal Model:CH3 wild-type mice
Dosage:1 and 15 mg/kg
Administration:Intraperitoneal injection; 1 and 15 mg/kg once
Result:Positively affected memory by inhibiting QR2.
体外研究：
S29434 (5-10 μM；24 h) 诱导 HepG2 细胞自噬。
产品资料
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