产品
编 号：F575915
分子式：C20H19N3O2S
分子量：365.45
分子式：C20H19N3O2S
分子量：365.45
产品类型
规格
价格
是否有货
结构图
CAS No: 736945-96-3
产品详情
生物活性：
TRPC3/6-IN-1 is a potent selectivity blocker of the canonical transient receptor channels (TRPC3/6), has block potency for hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively. TRPC3/6-IN-1 can be used for the research of chronic models of heart failure.
体内研究：
TRPC3/6-IN-1 (compound 3) has good pharmacokinetic in rats.Pharmacokinetic Parameters of TRPC3/6-IN-1 in rats .CompdDose(iv)(mg/kg)Cmax(iv)(ng/ml)CL(iv)(ml/min/kg)MRT(iv)(h)DNAUC(iv)(h?kg/L) %F
30.932501200.30.14~1
体外研究：
TRPC3/6-IN-1 has block potency for hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively.
TRPC3/6-IN-1 is a potent selectivity blocker of the canonical transient receptor channels (TRPC3/6), has block potency for hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively. TRPC3/6-IN-1 can be used for the research of chronic models of heart failure.
体内研究：
TRPC3/6-IN-1 (compound 3) has good pharmacokinetic in rats.Pharmacokinetic Parameters of TRPC3/6-IN-1 in rats .CompdDose(iv)(mg/kg)Cmax(iv)(ng/ml)CL(iv)(ml/min/kg)MRT(iv)(h)DNAUC(iv)(h?kg/L) %F
30.932501200.30.14~1
体外研究：
TRPC3/6-IN-1 has block potency for hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备