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编 号:F573020
分子式:C102H169N27O33
分子量:2301.59
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生物活性:
PEN (rat), one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.

体外研究:
Mouse PEN (mPEN) and rat PEN (rPEN) only differ by one residue at the N-terminal end, whereas human PEN (hPEN) is more divergent and has the sequence PEG instead of PEN.PEN binds and activates a GPCR in the brain.
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