产品
编 号:F572760
分子式:C15H11I3NNaO4
分子量:672.96
产品类型
结构图
CAS No: 55-06-1
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产品详情
生物活性:
Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
体外研究:
Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodiumpromotes growth, induces differentiation and regualtes metabolic effects.