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编 号:F570917
分子式:C27H39NaO8
分子量:514.58
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CAS No: 463356-00-5
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Sordarin is a potent diphthamide-dependent eEF2 inhibitor with antifungal properties. Sordarin targets eEF2 so as to inhibit protein translation by blocking eEF2-mediated translocation of tRNAs. Sordarin inhibits translation specifically in certain fungi (e.g. C.?albicans,?C.?glabrata, and?C.?neoformans) while unable to do so in some other fungal species (e.g. Candida parapsilosis and Candida lusitaniae).