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编 号：F568899
分子式：C18H19N3O6S
分子量：405.42
分子式：C18H19N3O6S
分子量：405.42
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CAS No: 3577-01-3
产品详情
生物活性：
Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration.
体内研究：
Respiration with and the uptake of succinate and ADP are measured in rabbit renal cortical mitochondria exposed for 2 to 6 h to 300 to 3,000 μg of Cefaloglycin (Cephaloglycin) per mL and then washed to remove the antibiotic. Cefaloglycin (Cephaloglycin) irreversibly reduces both respiration and succinate uptake. The pattern of in vitro injury of Cefaloglycin to mitochondrial substrate uptake and respiration evolves in a time-dependent and concentration-dependent manner.
体外研究：
Cefaclor to be comparable to Cephaloglycin in terms of in vitro activity against S. pyogenes and somewhat superior to Cephalexin.
Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration.
体内研究：
Respiration with and the uptake of succinate and ADP are measured in rabbit renal cortical mitochondria exposed for 2 to 6 h to 300 to 3,000 μg of Cefaloglycin (Cephaloglycin) per mL and then washed to remove the antibiotic. Cefaloglycin (Cephaloglycin) irreversibly reduces both respiration and succinate uptake. The pattern of in vitro injury of Cefaloglycin to mitochondrial substrate uptake and respiration evolves in a time-dependent and concentration-dependent manner.
体外研究：
Cefaclor to be comparable to Cephaloglycin in terms of in vitro activity against S. pyogenes and somewhat superior to Cephalexin.
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