产品
编 号:F568545
分子式:C10H12N2
分子量:160.22
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5mg
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10mg
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产品详情
生物活性:
Anabaseine is a non-selective nicotinic agonist. Anabaseine stimulates all AChRs, preferentially stimulates skeletal muscle and brain α7 subtypes. Anabaseine is also a weak partial agonist at α4β2 nAChRs.

体内研究:
Anabaseine (3.6 μmol/kg; subcutaneous injection) elevates ACh levels.

体外研究:
Anabaseine is a full agonist at α7 AChR in the central nervous system (CNS) and a full agonist at α1β1?δ and α1β1γδ (Torpedo) in the peripheral nervous system.Anabaseine acts as neuromuscular agonist on the frog rectus abdominis muscle (EC50: 0.25-0.74 μM).
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