产品
编 号：F567571
分子式：C22H23F2NO4
分子量：403.42
分子式：C22H23F2NO4
分子量：403.42
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 321995-62-4
产品详情
生物活性：
AGN 194078 is a selective RARα agonist with a Kd and EC50 of 3 and 112 nM, respectively.
体外研究：
AGN 194078 is a selective RARα agonist and binds to RARα with very high affinity, having a Kd value of 3 nM, while being unable to bind to RARβ and binding only very weakly (Kd=5600 nM) to RARγ. Furthermore, AGN 194078 maintains full transcriptional activity through RARα, with an EC50 value of 112 nM, but only activatedRARβ and RARγ with about 10% efficacy at the highest dose (1000 nM) tested.
AGN 194078 is a selective RARα agonist with a Kd and EC50 of 3 and 112 nM, respectively.
体外研究：
AGN 194078 is a selective RARα agonist and binds to RARα with very high affinity, having a Kd value of 3 nM, while being unable to bind to RARβ and binding only very weakly (Kd=5600 nM) to RARγ. Furthermore, AGN 194078 maintains full transcriptional activity through RARα, with an EC50 value of 112 nM, but only activatedRARβ and RARγ with about 10% efficacy at the highest dose (1000 nM) tested.
产品资料
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